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MYC and MET cooperatively drive hepatocellular carcinoma ... - NCBI
www.ncbi.nlm.nih.gov › PMC9700715
Nov 24, 2022 · This clinical observation drove us to explore the functionality of MYC and MET co-occurrence in vivo, combining hydrodynamic tail vein injection ...
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Nov 2, 2022 · E Tumors generated by intraductal lenti-Cre injections in B1P (n = 4) and B1P-Myc (n = 5) mice are analyzed via immunohistochemistry for CD3 ...
Dec 20, 2021 · In vivo studies show that MYC inhibition elicits a prominent anti-proliferative effect and sustained tumor regression while any alteration on ...
May 8, 2017 · MYC activation at modest levels has been frequently found in hepatocellular carcinoma. However, its significance in hepatocarcinogenesis has ...
Feb 19, 2021 · Our results indicate that TGFβ may function to inhibit HCC initiation but promote metastasis during HCC progression. Materials and methods ...
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Mar 9, 2023 · Following hydrodynamic injection, different levels of MYC expression in hepatocytes were confirmed by MYC immunohistochemistry and western blot ...
Our data suggest that φC31 integrase does not facilitate tumor formation in this C-MYC transgenic mouse model. However, in groups lacking φC31 integrase, ...
Feb 4, 2021 · Key Points. c-Myc controls HSC self-renewal, quiescence, and survival by regulating Nr4a1, Nr4a2, and Jmjd3 expression.
May 30, 2015 · In this study, we show that Myc overexpression is required for proper dedifferentiation of radial glial cells and for triggering the programmed ...
Nov 30, 2021 · New York, the country's most populous city, became the first U.S. city to open officially authorized injection sites — facilities that opponents ...