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MYC and MET cooperatively drive hepatocellular carcinoma ... - NCBI
www.ncbi.nlm.nih.gov › PMC9700715
Nov 24, 2022 · This clinical observation drove us to explore the functionality of MYC and MET co-occurrence in vivo, combining hydrodynamic tail vein injection ...
Nov 2, 2022 · E Tumors generated by intraductal lenti-Cre injections in B1P (n = 4) and B1P-Myc (n = 5) mice are analyzed via immunohistochemistry for CD3 ...
Dec 20, 2021 · In vivo studies show that MYC inhibition elicits a prominent anti-proliferative effect and sustained tumor regression while any alteration on ...
May 8, 2017 · MYC activation at modest levels has been frequently found in hepatocellular carcinoma. However, its significance in hepatocarcinogenesis has ...
Feb 19, 2021 · Our results indicate that TGFβ may function to inhibit HCC initiation but promote metastasis during HCC progression. Materials and methods ...
Jun 18, 2021 · Eighteen-week post plasmids injection, the mice injected with pT3-Myc-P2A-Cre-T2A-eGFP and SB plasmids will show tumor burden in liver, while ...
Our data suggest that φC31 integrase does not facilitate tumor formation in this C-MYC transgenic mouse model. However, in groups lacking φC31 integrase, ...
Nov 9, 2021 · To validate a functional requirement of Shp2 for Ras-Erk-Myc signaling, we co-injected a dominant active NRasG12V mutant together with Myc (Ras+ ...
Mar 9, 2023 · Following hydrodynamic injection, different levels of MYC expression in hepatocytes were confirmed by MYC immunohistochemistry and western blot ...
Nov 30, 2021 · New York, the country's most populous city, became the first U.S. city to open officially authorized injection sites — facilities that opponents ...
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